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Combination “AstraZeneca” – “Pfizer” increases the level of antibodies, says the study – Latest News

The combination

Mixed coronavirus vaccination, first with the AstraZeneca vaccine, then with the Pfizer / BioNTech vaccine, increases neutralizing antibody levels by six times compared to two doses of AstraZeneca, according to a South Korean study.

The study involved 499 medical staff: 100 of them received mixed doses, 200 received two doses of Pfizer / BioNTech and the rest received two doses of AstraZeneca.

All vaccinations resulted in neutralizing antibodies, which prevent the virus from entering the cells and multiplying.

The vaccine mix showed similar amounts of antibodies found in people who received two doses of the Pfizer / BioNTech vaccine.

A study published last month in the UK found that a dose of the Pfizer / BioNTech vaccine, given four weeks after a dose of the AstraZeneca vaccine, would produce a better immune response.

The South Korean study also analyzed neutralizing activity against major disturbing variants of the coronavirus, said the South Korea Disease Control and Prevention Agency.

None of the combinations demonstrated reduced neutralizing activity against the Alpha variant, first identified in Britain, but neutralization decreased by 2.5 to 6 times compared to the Beta, Gamma and Delta variants first discovered in South Africa and Brazil, respectively. and India. / REL

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